We support the World Health Organisation’s recommendation for exclusive breastfeeding for the first six months of life and continued breastfeeding along with the introduction of nutritionally adequate and safe complementary (solid) foods at 6 months together with continued breastfeeding up to two years of age and beyond.

From Tummy to Brain: How the Gut-Brain Connection Shapes Your Child


 

The Science Behind Gut-Brain Connection in Kids: How MFGM and Prebiotics Help Mood, Learning, and 24-Hour Comfort for Mums

Ever noticed how your toddler’s mood flips when their tummy’s off? As mums, we’ve all been there; one moment they’re giggling, and the next, they’re in full meltdown mode. As mums, we’ve all had those tough days. 

What many don’t realise is that your child’s tummy troubles may be directly to their mood, sleep, and even learning patterns. This powerful link is called the gut-brain connection, and it’s not just science talk; it’s something we see unfold every single day.

The truth is, digestion for toddler health isn’t just about avoiding tummy aches; it’s about nurturing emotional balance, brain development, and daily comfort.

Here’s what we’ll unpack together in this article:

  • How the gut-brain connection works in children and why it matters

  • The link between digestion and mood swings, how digestion affects mood in toddlers

  • Key nutrients like MFGM and prebiotics fuel both the tummy and the mind

  • Why a gentle gut sets the stage for better learning and behaviour

  • When to consider switching your child’s formula and signs to watch for

  • How supporting the gut means more peaceful days (and nights!) for both of you

So stay with us till the end as we explore more about how you can keep your child’s gut gentler. 

What is the Gut-Brain Connection in Children?


How digestion affects mood in toddlers

Did you know your child’s tummy and brain are constantly talking to each other? This is called the gut-brain connection. When their digestion is smooth, they feel calm and happy. But tummy issues like gas or constipation can lead to crankiness, poor sleep, and trouble focusing. That’s because their brain sends signals right down to their gut. So, if your child’s mood shifts suddenly, it might be their tummy trying to tell you something.1-5

Does mood affect digestion?

Yes—just like a sore tummy can cause moodiness, big emotions can upset the tummy too. If your toddler is anxious, overstimulated, or tired, their digestive system often reacts.

Studies show that stress and early emotional adversity can lead to ongoing digestive symptoms in children, especially if experienced in the early years. That’s why supporting emotional well-being and gut health early on is essential. 1-5

Key Nutrients that Support Tummy and Mind


The role of MFGM in brain development and behaviour

MFGM (Milk Fat Globule Membrane) is a natural part of milk that helps support your child’s brain, tummy, and mood.

What’s amazing is how closely MFGM and brain development are linked. It has nutrients that help your child build better memory, focus, and emotional control, skills that are growing every single day.6,7

But that’s not all. MFGM also supports gut health; we now know how important the gut is for learning and mood. A healthy tummy means better behaviour, more calm, and even better sleep. Here’s where the link between gut flora and learning comes in; when your child’s gut is in balance, it helps their brain learn and grow.6,7

Why Digestion is the Gateway to Learning


Gut flora and learning – more than just a tummy issue

Your child’s gut is home to trillions of tiny microbes called gut flora. This gut flora does more than help with digestion. They are key in brain development, learning, and even your child’s mood. The relationship between the gut and the brain is the gut-brain connection.

When gut flora is healthy, it supports clear thinking, better focus, and fewer mood swings. But when it's out of balance, it can affect how your child feels and learns.8

When to Rethink Your Children’s Milk Formula


Signs of child digestion problems and what to do next

As mums, we know our child best. If your little one seems extra fussy, spits up often, or has trouble passing stools, your instincts tell you something’s off. Sometimes, it’s not just a phase. It could be that their milk formula isn’t meeting their digestive needs. Understanding the signs early can make all the difference to your child’s comfort, mood, and development. 1, 9-14

Here are some signs to look out for:

  • Forceful or frequent vomiting

  • Spitting up large amounts after feeds

  • Green bile or blood in vomit

  • Watery, frequent stools (diarrhoea)

  • Constipation or hard stools

  • Bloating or visible discomfort

  • Colic-like crying spells for hours

  • Fussiness or crying after feeding

  • Refusing feeds or choking while feeding

  • Lethargy or seeming extra tired

If you notice any signs of digestive discomfort in your child, here’s how you can help:

Talk to your paediatrician: Always consult your child’s doctor to rule out any underlying medical conditions or food intolerances.

Consider switching formula milk: Look for one that includes:

  • MFGM (Milk Fat Globule Membrane): Supports your child’s brain development, emotional behaviour, and gut health.

  • Prebiotics like GOS & PDX: These plant-based fibres help balance gut flora, promote smoother digestion, and lead to softer stools.

Supporting the Gut-Brain Connection Brings 24-Hour Comfort

When your child’s gut is happy, the whole day (and night) feels easier for both of you. A balanced tummy supports calm moods, better sleep, sharper learning, and joyful moments. By paying close attention to signs of discomfort and choosing children's milk formula rich in MFGM and prebiotics like GOS and PDX, you’re not just easing tummy troubles; you’re actively supporting your child’s brain and emotional well-being.

Every child deserves a smooth, happy start to life. Sometimes, the simplest way to improve toddler digestion is by supporting the gut-brain connection with the right nutrition. When the tummy feels good, everything else follows.

Want a  Gentle Tummy and a Brighter Mood for Your Toddler?

Join the Enfamama A+ Club today and get expert tips, mum-approved routines, and the latest on toddler digestion, mood, and development, all tailored to your child’s needs.

Sign up for Enfamama A+ Club updates to receive free samples, exclusive offers, and gut-smart advice that helps improve toddler digestion and bring more smiles to your day.

References :

  1. Brown Health, The Gut-Brain Connection: What It Is and How to Help Children. https://www.health.harvard.edu/diseases-and-conditions/the-gut-brain-connection, Accessed June 2025.

  2. LifeBridge Health, Gut Feelings: Supporting Your Child’s Digestive and Emotional Health, https://www.lifebridgehealth.org/blogs/gut-feelings-supporting-your-childs-digestive-and-emotional-health, Accessed June 2025.

  3. Development and Psychopathology, Mind and gut: Associations
    between mood and gastrointestinal distress in children exposed to adversity, https://www.cambridge.org/core/journals/development-and-psychopathology/article/mind-and-gut-associations-between-mood-and-gastrointestinal-distress-in-children-exposed-to-adversity/D29E390A71A1E74CAD6955177CDFAE44, Accessed June 2025.

  4. PubMed, Mind and gut: Associations between mood and gastrointestinal distress in children exposed to adversity, https://pubmed.ncbi.nlm.nih.gov/30919798/, Accessed June 2025.

  5. JGH Open, Brain-immune-gut benefits with early life supplementation of milk fat globule membrane, https://pmc.ncbi.nlm.nih.gov/articles/PMC9260205/, Accessed June 2025.

  6. Journal of Functional Foods, The effect of supplementation with milk fat globule membranes on psychological health: A randomized clinical trial in healthy adults with moderate stress, https://www.sciencedirect.com/science/article/pii/S1756464623001858, Accessed June 2025.

  7. Frontiers in Pediatrics, Gut microbiota in various childhood disorders: Implication and indications, https://pmc.ncbi.nlm.nih.gov/articles/PMC9150060/, Accessed June 2025.

  8. Stanford Children’s Health, Gastrointestinal Problems, https://www.stanfordchildrens.org/en/topic/default?id=gastrointestinal-problems-90-P02216, Accessed June 2025.

  9. Foods, Prebiotics: Definition, Types, Sources, Mechanisms, and Clinical Applications, https://pmc.ncbi.nlm.nih.gov/articles/PMC6463098/, Accessed June 2025.

  10. Current Pediatric Research, Nutrition in preschoolers with emphasis on prebiotics: a review, https://www.currentpediatrics.com/articles/nutrition-in-preschoolers-with-emphasis-on-prebiotics-a-review-22611.html,  Accessed June 2025.

  11. Journal of Nutrition, Oligosaccharides from milk, https://doi.org/10.1093/jn/137.3.847S, Accessed June 2025.

  12. Pediatric Gastroenterology, Hepatology & Nutrition, Gastrointestinal health and immunity of milk formula supplemented with a prebiotic mixture of short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides (9:1) in healthy infants and toddlers: a systematic review with meta-analysis, https://www.pghn.org/DOIx.php?id=10.5223/pghn.2025.28.1.1,  Accessed June 2025. 

  13. Scandinavian Journal of Food and Nutrition, Galacto-oligosaccharides and bowel function, https://pmc.ncbi.nlm.nih.gov/articles/PMC2607002/, Accessed June 2025.

 

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